Download Installer Version 1.4.0 (66.6 MB)Compatible with Windows/Mac/Linux. Source included. Java 7 or higher required to run.
This version of DPS includes drug perturbations from the new CMAP LINCS L1000 dataset covering thousands of small molecules
Drug Pair Seeker (DPS) is a Java program that attempts to predict and prioritize pairs of drugs using the Connectivity Map dataset. Users can enter lists
of up and down differentially expressed genes from their own experiments to receive
a ranked list of drug combinations that would either reverse or aggravate the condition
of their cells or tissue using a simple formula shown below.
Please acknowledge DPS in your publications by citing the following reference:
Zhong Y, Chen EY, Liu R, Chuang PY, Mallipattu SK, Tan CM, Clark NR, Deng Y, Klotman PE, Ma'ayan A, He JC. Renoprotective effect of combined inhibition of angiotensin-converting enzyme and histone deacetylase. J Am Soc Nephrol. 2013 Apr;24(5):801-11
(c) 2013 DPS was developed by the Ma'ayan Laboratory at the Icahn School of Medicine at Mount Sinai, New York, NY
Try these other tools developed by the Ma'ayan Lab:
